Medical management of metastatic medullary thyroid cancer
نویسندگان
چکیده
منابع مشابه
Imaging Techniques for Metastatic Thyroid Medullary Cancer
Medullary thyroid carcinoma (MTC) originating from the calcitoninsecreting parafollicular cells is a relatively uncommon disease. It constitutes 3% to 10% of all thyroid malignancies (1). MTC may occur in sporadic or rarely familial form as a part of multiple endocrine neoplasia syndrome type 2A and 2B. The sporadic MTC is mostly detected on the basis of clinical symptoms. Calcitonin that is se...
متن کاملGenetic and Epigenetic of Medullary Thyroid Cancer
Medullary thyroid carcinoma (MTC) is an infrequent calcitonin-producing neuroendocrine tumor that initiates from the parafollicular C cells of the thyroid gland. Several genetic and epigenetic alterations are collaterally responsible for medullary thyroid carcinogenesis. In this review article, we shed light on all the genetic and epigenetic hallmarks of MTC. From the genetic perspective, RET, ...
متن کاملMedullary Thyroid Cancer: A Review
Thyroid cancer is a malignancy of the thyroid parenchymal cells. There are four main types of thyroid cancer: papillary thyroid cancer (PTC), follicular thyroid cancer (FTC), anaplastic thyroid carcinoma (ATC), and Medullary thyroid carcinoma (MTC). Medullary thyroid cancer (MTC) is a rare neuroendocrine tumor of the thyroid gland derived from parafollicular C-cells that produce calcitonin (CT...
متن کامل2012 European thyroid association guidelines for metastatic medullary thyroid cancer.
Distant metastases are the main cause of death in patients with medullary thyroid cancer (MTC). These 21 recommendations focus on MTC patients with distant metastases and a detailed follow-up protocol of patients with biochemical or imaging evidence of disease, selection criteria for treatment, and treatment modalities, including local and systemic treatments based on the results of recent tria...
متن کاملCurrent management of medullary thyroid cancer.
Medullary thyroid cancer accounts for 5%-10% of all thyroid cancers. The majority of medullary thyroid cancers are sporadic, but 20% of cases are a result of a germline mutation in the ret proto-oncogene. Hereditary medullary thyroid cancer can be seen as part of the multiple endocrine neoplasia syndrome type 2A or 2B or as part of familial medullary thyroid cancer. This article discusses the c...
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ژورنال
عنوان ژورنال: Cancer
سال: 2014
ISSN: 0008-543X
DOI: 10.1002/cncr.28858